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Fig. 1 | Respiratory Research

Fig. 1

From: Efficacy of budesonide/glycopyrronium/formoterol metered dose inhaler in patients with COPD: post-hoc analysis from the KRONOS study excluding patients with airway reversibility and high eosinophil counts

Fig. 1

Change in morning pre-dose trough FEV1 over 12–24 weeks (patients with non-reversible airways and EOS < 300 cells/mm3). Bars are LSM (95% SE). Data analyzed in the mITT population using an efficacy estimand. Treatment comparisons are RR (95% CI). BFF, budesonide/formoterol fumarate dihydrate; BGF, budesonide/glycopyrronium/formoterol fumarate dihydrate; BUD/FORM, budesonide/formoterol fumarate dihydrate; FEV1, forced expiratory volume in 1 s; GFF, glycopyrronium/formoterol fumarate dihydrate; LSM, least squares mean; mITT, modified intent-to-treat; SE, standard error

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