| Group Aa (N = 116) | Group Bb (N = 173) | P value |
---|---|---|---|
Physical characteristics | |||
 Gender (male ratio, %) | 44% | 52% | 0.2212 |
 Age (year) | 33.06 ± 17.50 | 50.68 ± 13.25 |  < 0.0001 |
 BMI (kg/m2) | 22.10 ± 3.43 | 24.06 ± 3.21 |  < 0.0001 |
Pre-existing conditions (with pre-existing disease ratio) | |||
 Pre-existing disease (%) | 19.0% | 38.2% | 0.0008 |
 DM (%) | 0% | 7.5% | 0.0063 |
 Hypertension (%) | 3.5% | 19.1% | 0.0002 |
 Coronary heart disease (%) | 3.5% | 6.9% | 0.3131 |
 Respiratory disease (%) | 3.5% | 5.2% | 0.6776 |
Others | |||
 Case type: (severe/critical ratio, %) | 4.3% | 29.5% |  < 0.0001 |
 Time from onset to virus RNA negative (day) | 14.72 ± 8.22 | 20.99 ± 9.34 |  < 0.0001 |
 Time from onset to admission (day) | 3.01 ± 3.03 | 5.22 ± 4.29 |  < 0.0001 |
 Length of hospitalization (day) | 19.17 ± 6.85 | 24.35 ± 9.70 |  < 0.0001 |
 Follow-up period from onset (day) | 67.78 ± 36.09 | 117.77 ± 14.24 |  < 0.0001 |
Symptoms | |||
 Fever (%) | 51.7% | 72.8% | 0.0004 |
 Fatigue (%) | 9.5% | 10.4% | 0.9554 |
 Dry cough (%) | 18.1% | 25.4% | 0.1871 |
 Cough (%) | 13.8% | 18.5% | 0.3724 |
 Expectoration (%) | 9.5% | 6.9% | 0.5739 |
 Diarrhea (%) | 0.9% | 5.8% | 0.0675 |
Treatment | |||
 Short term methylprednisolone therapy (%) | 5.17% | 32.3% |  < 0.0001 |
 Acetylcysteine (100%) | 41.4% | 71.7% |  < 0.0001 |
 Gamma globulin (100%) | 4.3% | 31.8% |  < 0.0001 |
 Invasive ventilator (100%) | 0% | 5.2% | 0.0315 |
 Non-invasive ventilator (100%) | 0.9% | 14.5% | 0.0002 |
Laboratory findings | |||
 Oxygenation index (PaO2/FiO2) | 463.15 ± 123.05 | 411.60 ± 130.24 | 0.0014 |
 Lactic acid (mmol/L) | 1.29 ± 0.45 | 1.34 ± 0.44 | 0.2963 |
 WBC (109/L) | 5.179 ± 2.04 | 4.82 ± 1.71 | 0.1174 |
 N (109/L) | 2.85 ± 1.47 | 3.00 ± 1.43 | 0.3689 |
 L (109/L) | 1.7659 ± 0.88 | 1.32 ± 0.59 |  < 0.0001 |
 HB (g/L) | 137.11 ± 15.43 | 138.28 ± 15.08 | 0.5240 |
 PLT (109/L) | 210.35 ± 65.32 | 188.19 ± 56.95 | 0.0025 |
 ALB (g/L) | 43.91 ± 3.18 | 42.64 ± 3.55 | 0.0021 |
 ALT (U/L) | 24.54 ± 26.74 | 26.32 ± 17.20 | 0.4918 |
 AST (U/L) | 28.34 ± 20.18 | 31.01 ± 13.97 | 0.1855 |
 LDH (U/L) | 267.37 ± 144.00 | 308.43 ± 191.53 | 0.0594 |
 CK (U/L) | 115.30 ± 194.97 | 103.05 ± 112.20 | 0.5729 |
 BUN (mmol/L) | 4.16 ± 1.41 | 4.09 ± 1.62 | 0.6789 |
 Cr (μmol/L) | 60.92 ± 17.81 | 68.75 ± 20.66 | 0.0010 |
 ESR (mm/h) | 23.01 ± 20.32 | 35.95 ± 23.00 |  < 0.0001 |
 D-Dimer (μg/mL) | 0.42 ± 0.37 | 0.52 ± 0.68 | 0.1732 |
 CRP (mg/dL) | 12.25 ± 25.58 | 23.96 ± 30.38 | 0.0008 |
 IL-6 (ng/L) | 11.27 ± 19.57 | 20.68 ± 30.70 | 0.0112 |
 PCT (ng/mL) | 0.12 ± 0.10 | 0.09 ± 0.08 | 0.0053 |
 CD4 cells (count/μL) | 771.89 ± 419.79 | 535.68 ± 276.76 |  < 0.0001 |
 Highest CRP (mg/dL) | 19.23 ± 30.71 | 47.81 ± 54.94 |  < 0.0001 |
 Highest IL-6 (ng/L) | 8.91 ± 11.92 | 45.62 ± 142.25 | 0.0099 |
 Highest PCT (ng/mL) | 0.29 ± 0.09 | 0.32 ± 0.08 | 0.0003 |
 Lowest CD4 cell (count/μL) | 700.81 ± 383.69 | 471.46 ± 274.76 |  < 0.0001 |
 Highest ESR (mm/h) | 32.00 ± 29.07 | 50.29 ± 30.70 |  < 0.0001 |
 Highest D-Dimer (μg/mL) | 0.63 ± 0.84 | 1.40 ± 3.11 | 0.0095 |
 Highest lactic acid (mmol/L) | 2.19 ± 0.93 | 2.62 ± 0.85 | 0.0001 |
 Lowest oxygenation index (PaO2/FiO2) | 379.97 ± 118.46 | 270.93 ± 124.19 |  < 0.0001 |