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Fig. 1 | Respiratory Research

Fig. 1

From: Neutralization of IL-33 modifies the type 2 and type 3 inflammatory signature of viral induced asthma exacerbation

Fig. 1

Biomarkers of allergic lung inflammation are augmented in allergic-OVA mice infected with RSV. A Mice were intranasally infected with purified RSV-A2 24 h following final OVA airway challenge. Four groups of mice were included in each experiment; saline-treated alone (Saline), RSV-infected (RSV), OVA-treated alone (OVA), and OVA-treated, RSV-infected (OVA-RSV). B, C Total lung RNA was examined for RNA expression of common allergic markers using a RT2 PCR array. For all experiments, N = 3–4 mice/group. ANOVA was used to determine of statistical significance and Kruskal–Wallis post-test analysis was used to determine the statistical significance between groups. *Indicates P < 0.05

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