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Table 5 ORs and 95% CIs according to combined effect of lung disease history, family cancer history and environmental exposure index score among non-smokers

From: Combined effects of lung disease history, environmental exposures, and family history of lung cancer to susceptibility of lung cancer in Chinese non-smokers

Risk factors#

Without family cancer history

With family cancer history

Without lung disease history

With lung disease history

Without lung disease history

With lung disease history

Cs/cnt

OR (95%CI)

Cs/cnt

OR (95%CI)

Cs/cnt

OR (95%CI)

Cs/cnt

OR (95%CI)

EEI-1

        

Low

89/278

1.000

7/19

1.178 (0.469, 2.959)

19/76

0.960 (0.543, 1.699)

4/7

1.788 (0.497, 6.434)

Intermediate

198/209

2.715 (1.977, 3.729)

17/7

7.960 (3.111, 20.367)

41/44

2.792 (1.684, 4.628)

5/3

5.916 (1.336, 26.199)

High

253/87

7.881 (5.547, 11.198)

34/5

22.306 (8.335, 59.700)

94/29

9.797 (5.990, 16.023)

6/3

6.729 (1.577, 28.718)

p value (test for trend)

 < 0.001

EEI-2

        

Low

89/278

1.000

7/19

1.178 (0.469, 2.959)

19/76

0.960 (0.543, 1.699)

4/7

1.788 (0.497, 6.434)

Intermediate

198/209

2.715 (1.977, 3.729)

17/7

7.960 (3.111, 20.367)

41/44

2.792 (1.684, 4.628)

5/3

5.916 (1.336, 26.199)

High

253/87

7.881 (5.547, 11.198)

34/5

22.306 (8.335, 59.700)

94/29

9.797 (5.990, 16.023)

6/3

6.729 (1.577, 28.718)

p value (test for trend)

 < 0.001

  1. The bold values represent P values less than 0.05
  2. ORs were adjusted for sex, age, marriage, education, occupation
  3. Cs/cnt Case/ControlOR odds ratio, CI confidence interval
  4. #The indicated subgroups were categorized by the tertiles of environmental exposure index (EEI) in the cases and controls