Table 3 Univariate Cox regression analysis
From: A proposed prognostic prediction score for pleuroparenchymal fibroelastosis
Variables | HR (95% CI) | P value |
|---|---|---|
Age (> 65 year) | 1.53 (0.85–2.76) | 0.15 |
Gender (male) | 0.88 (0.49–1.57) | 0.66 |
Underlying disease (yes) | 0.59 (0.18–1.92) | 0.38 |
Smoking history (yes) | 0.96 (0.53–1.75) | 0.91 |
History of pneumothorax (yes) | 2.98 (1.61–5.51) |  < 0.001 |
BMI (< 18 kg/m2) | 2.32 (1.29–4.17) |  < 0.01 |
Fine crackles (yes) | 1.38 (0.78–2.42) | 0.27 |
Finger clubbing (yes) | 0.53 (0.13–2.18) | 0.38 |
mMRC (2–4) | 1.76 (0.98–3.15) | 0.058 |
KL-6 (> 550 U/ml) | 2.62 (1.46–4.7) |  < 0.01 |
SP-A (> 50 ng/ml) | 1.34 (0.62–2.89) | 0.46 |
SP-D (> 270 ng/ml) | 1.39 (0.76–2.55) | 0.29 |
%FVC (< 65%) | 2.01 (1.12–3.59) | 0.019 |
%RV/TLC (> 125%) | 1.00 (0.52–1.92) | 0.99 |
%DLCO (< 85%) | 1.99 (1.00–3.94) | 0.05 |
6MT distance (< 270 m) | 1.64 (0.76–3.56) | 0.21 |
6MT lowest SpO2 (< 92%) | 1.16 (0.56–2.41) | 0.69 |
Flat chest index (< 0.57) | 1.73 (0.99–3.05) | 0.056 |
UIP pattern in the lower lobes (yes) | 1.57 (0.89–2.76) | 0.12 |
ILD in the lower lobes (yes) | 2.50 (1.21–5.19) | 0.014 |