Table 2 Differences in MBL, ficolin-2 and immunoglobulin subclass concentrations and deficiencies according to the duration of glucocorticoid treatment for the index exacerbation (14 days vs. 5 days)
14d steroids | 5d steroids | p-value* | |
|---|---|---|---|
MBL, median (IQR), ng/mL | 1262 (2528) | 1409 (2324) | 0.95 |
MBL < 500 ng/mL, n (%) | 32 (33) | 24 (29) | 0.67 |
Ficolin-2, median (IQR), ng/mL | 5422 (3692) | 5302 (2544) | 0.70 |
Ficolin-2 < 25% Quantile, n (%) | 25 (26) | 20 (24) | 0.94 |
Total IgG, median (IQR), g/L | 8.8 (3.8) | 9.8 (3.1) | < 0.01 |
IgG deficiency, n (%) | 36 (38) | 13 (16) | < 0.01 |
IgG1, median (IQR), g/L | 5.0 (2.6) | 6.2 (2.3) | < 0.01 |
IgG1 deficiency, n (%) | 47 (49) | 18 (22) | < 0.01 |
IgG2, median (IQR), g/L | 2.7 (1.4) | 2.9 (1.8) | 0.13 |
IgG2 deficiency, n (%) | 9 (9) | 7 (9) | 1.00 |
IgG3, median (IQR), g/L | 0.412 (0.29) | 0.47 (0.40) | 0.02 |
IgG3 deficiency, n (%) | 13 (14) | 7 (9) | 0.41 |
IgG4, median (IQR), g/L | 0.302 (0.46) | 0.41 (0.65) | 0.04 |
IgG4 deficiency, n (%) | 13 (14) | 10 (12) | 0.97 |
IgA, median (IQR), g/L | 2.3 (1.7) | 2.56 (1.3) | 0.34 |
IgA deficiency, n (%) | 6 (6) | 1 (1) | 0.18 |
IgA1, median (IQR), g/L | 2.0 (1.5) | 2.1 (1.1) | 0.34 |
IgA1 deficiency, n (%) | 6 (6) | 1 (1) | 0.18 |
IgA2, median (IQR), g/L | 0.49 (0.42) | 0.55 (0.39) | 0.27 |