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Fig. 4 | Respiratory Research

Fig. 4

From: Upregulation of leukocyte immunoglobulin-like receptor B4 on interstitial macrophages in COPD; their possible protective role against emphysema formation

Fig. 4

The deficiency of LILRB4 aggravated emphysematous lesions in the mouse elastase-induced emphysema model. a Representative hematoxylin/eosin-stained histological images of the lungs from wild-type or LILRB4−/− mice on day 21 after PBS or elastase intranasal administration. Scale bar: 500 μm. b Mean liner intercepts calculated by analyzing histological images on day 21 after administration. c Representative chest CT images of wild-type mice (left) and LILRB4−/− mice (right) on day 21 after intranasal administration of elastase. d Low attenuation area (LAA) of CT images on day 21 after administration. Data are presented as median with a dot for each sample. The Steel–Dwass test was used for nonparametric multiple comparisons among the groups. N = 5 to 10 per groups. WT wild-type mice, KO LILRB4-deficient mice, MLI mean liner intercept, LAA low attenuation area

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