Figure 5

Analysis of the cellular pulmonary immune response in immunocompetent SP-A deficient (KO) and Wild-Type (WT) mice. Mononuclear cells were isolated from the lungs of KO and WT mice with no experimental exposure to P. murina. CD4+ and CD8+ T cell populations were identified by cell surface antibody labeling and quantitated by flow cytometry. A. Mean ± the SEM of the number cells per mouse. B. Mean percentage of CD4+ and CD8+ T cells per mouse. There were 10 mice in the KO group and 8 mice in the WT group. * p < 0.01 KO vs. WT as determined by t test.