Table 2 Characteristics of subjects (N = 11,212) with COPD exacerbation by vital status at 90-days after admission*
From: Impact of statins and ACE inhibitors on mortality after COPD exacerbations
Variables | Alive Within 90 days (N = 9825) | Dead within 90-days (N = 1387) | P-value |
|---|---|---|---|
Age, years mean (SD) | 73.8 (5.6) | 75.0 (5.8) | <0.0001 |
Men | 9627 (98) | 1366 (98) | 0.2 |
Race/ethnicity | |||
White | 8059 (82) | 1167 (84) | |
Black | 1276 (13) | 162 (12) | |
Hispanic | 269 (3) | 31 (2) | 0.1 |
Other/unknown | 221 (2) | 27 (2) | |
Married | 4788 (49) | 687 (50) | 0.3 |
Comorbid conditions | |||
Myocardial infarction | 1335 (14) | 189 (14) | 0.97 |
Congestive heart failure | 4800 (49) | 741 (53) | 0.001 |
Peripheral vascular disease | 2703 (28) | 404 (29) | 0.2 |
Stroke | 1012 (10) | 153 (11) | 0.4 |
Peptic ulcer | 1411 (14) | 173 (12) | 0.06 |
Rheumatologic disease | 511 (5) | 62 (5) | 0.2 |
Diabetes | 3020 (31) | 386 (28) | 0.03 |
Diabetes with complications | 1322 (13) | 153 (11) | 0.01 |
Liver disease, mild | 291 (3) | 56 (4) | 0.03 |
Liver disease, moderate | 41(0.4) | 14 (1) | 0.003 |
Hemiplegia | 375 (4) | 57 (4) | 0.6 |
Dementia | 415 (4) | 65 (5) | 0.4 |
Renal disease | 943 (10) | 180 (13) | <0.0001 |
Any malignancy | 3068 (31) | 500 (36) | <0.0001 |
Metastatic solid tumor | 410 (4) | 123 (9) | <0.0001 |
Medications | |||
ACE Inhibitor/ARB | 3249 (33) | 335 (24) | <0.0001 |
Statin | 2113 (22) | 173 (13) | <0.0001 |
Cardiac, count (SD) | 4.8 (4.0) | 4.7 (4.0) | 0.7 |
Respiratory, count (SD) | 4.4 (3.7) | 4.4 (3.7) | 0.7 |
Diabetic, count (SD) | 3.0 (2.2) | 3.0 (2.2) | 0.5 |
Inhaled corticosteroids | 2667 (27) | 394 (28) | 0.3 |
Oral corticosteroids | 2650 (27) | 390 (28) | 0.4 |