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Figure 2 | Respiratory Research

Figure 2

From: Macrophage derived chemokine (CCL22), thymus and activation-regulated chemokine (CCL17), and CCR4 in idiopathic pulmonary fibrosis

Figure 2

Correlations between BAL fluid CCL22 and CCR4-positive alveolar macrophages and lymphocytes in all patients examined. To further elucidate the roles of the chemokines in recruiting cells to the lungs in fibrotic lung diseases, we analyzed CCR4-positive BAL fluid cell subpopulations by flow cytometry in IPF. CCL22 levels significantly correlated with the number of CCR4-positive alveolar macrophages (A). CCL22 levels in IPF patients were significantly correlated with the number of CCR4-positive alveolar macrophages and lymphocytes. These correlations were not observed between these subpopulations and BAL fluid CCL17 levels.

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