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Figure 1 | Respiratory Research

Figure 1

From: Nicotine enhances murine airway contractile responses to kinin receptor agonists via activation of JNK- and PDE4-related intracellular pathways

Figure 1

Nicotine-induced effects on kinin receptor-mediated airway contractions. Tracheal segments were cultured for 1 day (A, B), 2 days (C, D) or 4 days (E, F) in presence of vehicle (Control, 0.1% DMSO) or nicotine (Nic, 1 or 10 μM). Contractions were induced by des-Arg9-bradykinin (D-A-BK; A, C, E) or bradykinin (BK; B, D, F). Each data point is derived from 15-22 experiments and data is presented as mean ± S.E.M. Statistical analysis was performed using two-way ANOVA with Bonferroni's post-test. Control vs Nic. * P < 0.05; ** P < 0.01; *** P < 0.001.

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Respiratory Research

ISSN: 1465-993X

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