Figure 5
From: A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice
Effect of iloprost on alteration of lung mechanics induced by bleomycin (Bleo). Measurement of lung function was performed at 21 days after injecting 2 mg/kg of bleomycin. Decrease in static compliance (Cst) (A) and increase in tissue elastance (H) (B) were significantly attenuated in the mice treated with Bleo+iloprost. Results are expressed as mean ± SEM, n = 10-12 mice per group, * P < 0.05, ** P < 0.01.