Figure 6

Comparison of nasal epithelium membrane cholesterol content inCftr+/+ andCftr+/- mice. A) Representative traces of membrane cholesterol determination in excised nasal epithelium from Cftr +/+ (wt) mice and Cftr +/- mice. B) Quantification of electrochemical membrane cholesterol determination between Cftr +/+ (wt) nasal tissue and Cftr +/- nasal tissue. Responses are reported relative to wt response (response ratio) to indicate the fold-difference in response. Error bars represent SEM, n = 4 for each. Significance determined by t test. *p = 0.008.