Effect of β2-adrenergic receptor gene (ADRB2) 3′ untranslated region polymorphisms on inhaled corticosteroid/long-acting β2-adrenergic agonist response

Table 1 Allele frequencies

	White^a	Asian	Black	Mixed	Total
Patients, n	1,634	156	21	439	2,250
No. of alleles determined Alleles determined, %	3,216	310	38	820	4,384
9a	0.1	–	–	0.1	0.1
10a	3.6	13.2	21.1	3.5	4.4
11a	35.6	2.3	13.2	19.5	30.0
12a	23.5	31.3	7.9	28.9	24.9
12b	<0.1	–	–	–	<0.1
12d	–	–	–	0.1	<0.1
12e	–	0.3	–	–	<0.1
13a	0.9	1.0	2.6	0.6	0.8
13b	30.0	40.6	39.5	37.3	32.2
13c	<0.1	–	5.3	1.1	0.3
14b	6.0	10.6	10.5	8.5	6.8
15b	0.1	0.6	–	0.2	0.1
16b	0.2	–	–	–	0.1
No. of alleles undetermined	52	2	4	58	116

^aWhites of European descent.
Allele frequency calculated from the number of alleles determined. Where the allele was not observed at all, ‘-’ was used.

ISSN: 1465-993X