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Table 3 Prevalence of CFTR mutations in Caucasian COPD and control subjects

From: Impact of heterozygote CFTR Mutations in COPD patients with Chronic Bronchitis

Study population

With mutation

Without mutation

P Value

COPD N = 127

 

  Any mutation

5 (3.9%)

122 (96.1%)

0.92

  F508del

2 (1.5%)

125 (98.5%)

0.63

  Non-F508del

3 (2.4%)

124 (97.6%)

0.63

Controls N = 32,900

 

  Any mutation

1,356 (4.1%)

31,544 (95.9%)

 

  F508del

880 (2.7%)

32,020 (97.3%)

 

  Non-F508del

476 (1.4%)

32,424 (98.6%)

 
  1. P-values presented are Chi-square analyses compared to general Caucasian population.