From: Impact of heterozygote CFTR Mutations in COPD patients with Chronic Bronchitis
Study population | With mutation | Without mutation | P Value |
---|---|---|---|
COPD N = 127 |  | ||
  Any mutation | 5 (3.9%) | 122 (96.1%) | 0.92 |
  F508del | 2 (1.5%) | 125 (98.5%) | 0.63 |
  Non-F508del | 3 (2.4%) | 124 (97.6%) | 0.63 |
Controls N = 32,900 |  | ||
  Any mutation | 1,356 (4.1%) | 31,544 (95.9%) |  |
  F508del | 880 (2.7%) | 32,020 (97.3%) |  |
  Non-F508del | 476 (1.4%) | 32,424 (98.6%) |  |