Figure 2From: Prevention of hyperoxia-induced bronchial hyperreactivity by sildenafil and vasoactive intestinal peptide: impact of preserved lung function and structureEquivalent doses of methacholine required to cause a 50% elevation in airway resistance (ED 50 , panel A) and the end-expiratory lung volumes (EELV, panel B) measured in rats exposed to room air (Group C) subjected to hyperoxia without any additional treatment (Group HC) and hyperoxic rats treated either with sildenafil (Group HS) or VIP (Group HV). *: p < 0.05 vs. Group C, #: p < 0.05 vs. Group HC.Back to article page