Figure 5From: SP-A binds alpha1-antitrypsin in vitro and reduces the association rate constant for neutrophil elastaseTurnover numbers per inactivation. Turnover numbers were determined plotting residual enzyme activity/initial enzyme activity versus initial inhibitor concentration/initial enzyme activity. A: (1) native α1-AT, (2) deglycosylated α1-AT, (3) Z α1-AT, (4) native α1-AT coupled with deglycosylated and boiled SP-A, (5) deglycosylated α1-AT coupled with deglycosylated SP-A, (6) deglycosylated α1-AT coupled with deglycosylated and boiled SP-A, (7) native α1-AT coupled with boiled SP-A and (8)native α1-AT coupled with SP-A sugar chains. B: (9) native α1-AT coupled with native SP-A and (10) Z α1-AT coupled with native SP-A, (11) deglycosylated α1-AT coupled with native SP-A, (12) deglycosylated α1-AT coupled with boiled SP-A, (13) deglycosylated α1-AT coupled with SP-A sugar chains and (14) native α1-AT coupled with deglycosylated SP-A.Back to article page