Figure 2

Prophylactic efficacy of VN04-2- and VN04-3-huG1 in mice. Mice were challenged with a lethal dose (10 MLD₅₀) of fully virulent A/Vietnam/1203/04 24 h after the introduction of 1, 5, or 10 mg/kg bodyweight of antibody. The percentage of initial body weight after challenge is indicated for VN04-2-huG1 (A) and VN04-3-huG1 (B) periodically over 15 days. Each data point represents the average of 5 mice. Survival of challenged mice was observed for 21 days after challenge and indicates the level of protection from mortality (C).