Table 4 CYP24A1 haplotype transmission results in 213 families of the German Asthma Family Study. Haplotype was formed from all SNPs with p < 0.05 in the TDT (table 2).
| Â | Â | h1 | h2 | h3 | h4 | h5 | h6 | h7 |
|---|---|---|---|---|---|---|---|---|
SNP | rs2296241 | G | A | A | G | G | A | A |
| Â | rs17219315 | A | A | A | A | A | A | G |
| Â | rs2762942 | A | A | A | G | A | A | A |
| Â | rs2248137 | C | G | C | C | G | G | G |
| Â | rs2248359 | C | T | C | C | T | C | T |
frequency | Â | 0,40 | 0,31 | 0,15 | 0,04 | 0,03 | 0,03 | 0,02 |
asthma | Z value | 3,42 | -2,11 | -1,43 | 0,10 | NA | NA | NA |
| Â | P value | 0,001 | 0,035 | 0,153 | 0,919 | NA | NA | NA |
log(IgE) | Z value | 3,19 | -1,97 | -1,26 | -0,46 | 0,71 | NA | -0,79 |
| Â | p value | 0,001 | 0,049 | 0,208 | 0,645 | 0,478 | NA | 0,432 |
log(25-OH-D3) | Z value | 2,85 | -2,25 | -1,03 | 0,08 | 1,59 | NA | -0,22 |
| Â | P value | 0,004 | 0,025 | 0,305 | 0,935 | 0,112 | NA | 0,823 |
log(1,25-OH2-D3) | Z value | 2,83 | -1,94 | -1,38 | 0,10 | 1,50 | NA | -0,09 |
| Â | p value | 0,005 | 0,052 | 0,167 | 0,922 | 0,134 | NA | 0,932 |