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Figure 1 | Respiratory Research

Figure 1

From: Glycyrrhizin, inhibitor of high mobility group box-1, attenuates monocrotaline-induced pulmonary hypertension and vascular remodeling in rats

Figure 1

Scheme of animal experimental timeline. Pulmonary hypertension was induced by a single subcutaneous injection of MCT (60 mg/kg). The GLY (50 mg/k) was intraperitoneally treated once daily immediately after MCT injection for 4 weeks or 6 weeks in the MCT + GLY group, while normal saline was injected in the MCT group. Hemodynamic changes, RV hypertrophy, histological changes of lung, micro-PET, and survival rate were measured at the end of the animal experiment.

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Respiratory Research

ISSN: 1465-993X

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