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Table 1 Lung injury scores in all groups in vivo

From: RETRACTED ARTICLE: Activation of c-Src tyrosine kinase mediated the degradation of occludin in ventilator-induced lung injury

Group

Alveolar congestion

Hemorrhage

Infiltration of neutrophils

Alveolar wall thickness

Total score

Group C

0

0

0

0

0

Group M

0.33 ± 0.52

0

0.67 ± 0.52

0.5 ± 0.55

1.33 ± 1.51

Group M + P

0.33 ± 0.52

0

0.33 ± 0.52

0.33 ± 0.52

1.00 ± 1.26

Group H

1.67 ± 0.82

0

1.33 ± 0.52

1.5 ± 0.55

4.50 ± 0.84*&

Group H + P

0.50 ± 0.55

0

0.50 ± 0.55

0.67 ± 0.82

1.67 ± 1.21#

  1. Data are presented as mean ± SD. *P < 0.05 versus Group C; #P < 0.05 versus Group H; &P < 0.05 versus Group M. Lung injury was scored in each sample (n = 6 for each group) according to the following four items: alveolar congestion, hemorrhage, infiltration or aggregation of neutrophils in airspace or the vessel wall, and thickness of the alveolar wall/hyaline membrane formation. Each item was graded according to a 5-point scale: 0, minimal (little) damage; 1, mild damage; 2, moderate damage; 3, severe damage; and 4, maximal damage.