Serum extracellular vesicular miR-21-5p is a predictor of the prognosis in idiopathic pulmonary fibrosis

Respiratory Research

Table 6 The association between miR-21-5p of and mortality in IPF patients during 30 months using Univariate Cox Hazard model analyses with adjustment for each of the four parameters

The factor for adjustment	Univariate
The factor for adjustment	HR (95 % CI)^a	P value
Sex	1.16 (1.04–1.27)	0.008
Age	1.12 (1.003–1.24)	0.04
Emphysematous lesion detected by CT	1.19 (1.04–1.46)	0.01
KL-6	1.45 (1.15–1.83)	0.002
% predicted VC	1.16 (1.04–1.29)	0.01

Bold represents p < 0.05
HR hazard ratio, CI confidence interval, KL-6 Krebs von den Lungen-6 VC vital capacity
^aA unit hazard ratio (hazard ratio per one copy/SI in normalized serum EV miR-21-5p) is shown

ISSN: 1465-993X