Fig. 2From: Atrial natriuretic peptide protects against bleomycin-induced pulmonary fibrosis via vascular endothelial cells in miceANP attenuates inflammation in the lungs induced by BLM administration. Numbers of total cells (a), macrophages (b), neutrophils (c), and lymphocytes (d) in bronchoalveolar lavage (BAL) fluid on Day 7 after BLM administration. Values represent means ± SEMs (n = 5 mice per group). *p < 0.05. Lung sections from normal control mice (e), BLM-treated mice receiving vehicle (f), and BLM-treated mice receiving ANP treatment (g) obtained 7 days after BLM administration were stained with Mac-3. Representative images are shown at 200× magnification. h Mac-3–positive cells were counted in ten high-power fields (HPF). The data are expressed as means ± SE (in normal control group, n = 4; in the other groups, n = 5. *p < 0.05)Back to article page