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Fig. 4 | Respiratory Research

Fig. 4

From: Beclomethasone dipropionate and formoterol fumarate synergistically interact in hyperresponsive medium bronchi and small airways

Fig. 4

Graphical representation of Unified Theory analysis for BDP/FF combination administered at 100:6 concentration-ratio reporting the logarithmic Combination Index plot (a and b) and the normalized isobologram (c and d) in non-sensitized (a and c) and passively sensitized (b and d) human small airways (PCLS) submaximally contracted by histamine. Points represent the mean ± SEM of n = 5 bronchioles from different subjects; the labels of points report the weight/weight ratio (ng/ng) between BDP and FF. BDP: beclomethasone dipropionate; CI: Combination Index; Fa: fraction affected; FF: formoterol fumarate. Fu: fraction unaffected; PCLS: precision cut lung slices

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Respiratory Research

ISSN: 1465-993X

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