From: Smoking is associated with quantifiable differences in the human lung DNA virome and metabolome
Demographics | Smokers (n = 20) | Nonsmokers (n = 10) | Statistical Differences |
---|---|---|---|
Age, yr | 63.7 (58.5–67.2) | 36.2 (28.3–41.9) | p < 0.00001 |
Gender |  |  | p < 0.3980b |
 Male | 13 (65%) | 8 (80%) |  |
 Female | 7 (35%) | 2 (20%) |  |
Height, cm | 172.7 (165.1–179.1) | 176.5 (173.4–181.6) | p < 0.3125 |
Weight, kg | 79.8 (69.4–91.6) | 85.5 (75.1–101.2) | p < 0.6560 |
Race |  |  | p < 0.0037 b |
 White | 19 (95%) | 5 (50%) |  |
 Other | 1 (5%) | 5 (50%) |  |
Pulmonary Function Testinga | |||
 FVC (% Predicted) | 96.9 (90.2–102.8) | 96.0 (90.0–103.7) | p < 0.8337 |
 FEV1 (% Predicted) | 94.1 (86.7–104.2) | 97.1 (86.2–103.4) | p < 0.9840 |
 FEV1/FVC | 71.7 (69.9–78.4) | 83.5 (77.7–84.3) | p < 0.0220 |
 DLCO (% Predicted) | 91.0 (79.3–99.0) | 94.0 (82.0–98.0) | p < 0.4593 |
BAL Immune Cell Counts (%) | |||
 Macrophages | 90.8 (87.8–94.8) | 90.8 (86.0–93.5) | p < 0.9840 |
 Lymphocytes | 6.2 (3.9–8.7) | 6.6 (5.1–11.5) | p < 0.5552 |
 Neutrophils | 1.8 (1.3–2.9) | 1.3 (1.2–1.6) | p < 0.1645 |
 Eosinophils | 0.3 (0.1–0.6) | 0.2 (0.1–0.3) | p < 0.2670 |