Table 3 Most common extrapulmonary manifestations of PID (adapted from JC Aldave, JFM) [27]
From: Primary immunodeficiency diseases in lung disease: warning signs, diagnosis and management
MOST COMMON EXTRAPULMONARY MANIFESTATIONS OF PID | N (Composition of panel) | Votes in agreement (%) | Degree of agreement |
|---|---|---|---|
Recurrent or complicated sinusitis | 43 (AI, AP, PI, PP) | 100.0 | Unanimity |
Recurrent or complicated otitis | 43 (AI, AP, PI, PP) | 93.0 | Consensus |
Other extrapulmonary infections requiring admission | 43 (AI, AP, PI, PP) | 88.4 | Consensus |
Ectodermal dysplasia | 43 (AI, AP, PI, PP) | 72.1 | Majority |
Chronic diarrhea or malabsorption | 43 (AI, AP, PI, PP) | 93.0 | Consensus |
Difficult-to-treat giardiasis | 43 (AI, AP, PI, PP) | 93.0 | Consensus |
Autoimmune cytopenias or other autoimmunity | 43 (AI, AP, PI, PP) | 93.0 | Consensus |
Lymphadenopathies and hepatosplenomegaly | 43 (AI, AP, PI, PP) | 97.7 | Consensus |
Related cancers, especially associated with viruses | 43 (AI, AP, PI, PP) | 83.7 | Consensus |
Family history of ID or consistent manifestations | 43 (AI, AP, PI, PP) | 88.4 | Consensus |
Post-vaccinal infections | 43 (AI, AP, PI, PP) | 79.1 | Majority |