From: Aminoguanidine affects systemic and lung inflammation induced by lipopolysaccharide in rats
Parameters | Sample | LPS/Ctrl | AG/LPS | ||
---|---|---|---|---|---|
50 | 100 | 150 | |||
Total nitrite concentration | Serum | 238 | 93 | 79 | 57 |
BALF | 125 | 78 | 78 | 69 | |
Total WBC count | Blood | 141 | 91 | 85 | 77 |
BALF | 182 | 97 | 86 | 73 | |
Neutrophils | Blood | 138 | 87 | 83 | 80 |
BALF | 126 | 100 | 92 | 95 | |
Lymphocytes | Blood | 142 | 93 | 86 | 75 |
BALF | 175 | 97 | 88 | 74 | |
Monocytes | Blood | 155 | 88 | 82 | 73 |
Macrophages | BALF | 320 | 96 | 78 | 56 |
Eosinophils | Blood | 109 | 108 | 100 | 91 |
BALF | 150 | 85 | 100 | 83 | |
MDA concentration | Serum | 240 | 86 | 62 | 53 |
BALF | 623 | 71 | 68 | 44 | |
Total thiol content | Serum | 26 | 106 | 162 | 232 |
BALF | 16 | 86 | 124 | 368 | |
SOD activity | Serum | 10 | 292 | 370 | 585 |
BALF | 13 | 295 | 468 | 528 | |
CAT activity | Serum | 33 | 133 | 165 | 214 |
BALF | 8 | 263 | 398 | 583 | |
IL-4 | BALF | 42 | 101 | 155 | 222 |
IFN-γ | BALF | 293 | 82 | 70 | 45 |
TGF-β1 | BALF | 281 | 86 | 73 | 46 |
PGE2 | BALF | 301 | 79 | 68 | 42 |
Interstitial inflammation | Lung tissue | 732 | 100 | 90 | 63 |
Lymphoid infiltration | Lung tissue | 666 | 79 | 75 | 49 |