From: Chitotriosidase: a biomarker of activity and severity in patients with sarcoidosis
Sarcoidosis population | Controls | p-value | |
---|---|---|---|
N° | 694 | 101 | |
Male (%) | 270 (39) | 34 (33) | 0.1310 |
Age (years) | 55.8 ± 12.8 | 52.2 ± 17.2 | 0.2065 |
Smoking history (pack/year) | 4.4 ± 9.7 | 5.1 ± 11.6 | 0.3457 |
• Current (%) | 49 (7) | 10 (10) | 0.1199 |
• Former (%) | 225 (32.4) | 25 (25) | 0.1199 |
• Never (%) | 420 (60.5) | 66 (66) | 0.1199 |
Biomarkers determination (basal sampling) | |||
• Chitotriosidase nmol/ml/h | 175.4 ± 89.4 | 34.2 ± 13.8 | < 0.0001 |
• ACE UI/ml | 48.5 ± 26.7 | 34.3 ± 21.8 | 0.0014 |
• Lysozyme mg/dl | 5.4 ± 2.3 | 4.6 ± 2.1 | 0.0524 |