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Table 1 Demographic features, smoking status and biomarker assessment in the sarcoidosis cohort and healthy controls

From: Chitotriosidase: a biomarker of activity and severity in patients with sarcoidosis

 

Sarcoidosis population

Controls

p-value

694

101

 

Male (%)

270 (39)

34 (33)

0.1310

Age (years)

55.8 ± 12.8

52.2 ± 17.2

0.2065

Smoking history (pack/year)

4.4 ± 9.7

5.1 ± 11.6

0.3457

 • Current (%)

49 (7)

10 (10)

0.1199

 • Former (%)

225 (32.4)

25 (25)

0.1199

 • Never (%)

420 (60.5)

66 (66)

0.1199

Biomarkers determination (basal sampling)

 • Chitotriosidase nmol/ml/h

175.4 ± 89.4

34.2 ± 13.8

< 0.0001

 • ACE UI/ml

48.5 ± 26.7

34.3 ± 21.8

0.0014

 • Lysozyme mg/dl

5.4 ± 2.3

4.6 ± 2.1

0.0524