Clinical characteristics | All patients (n = 95) | Disease severity | Composite endpoint | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
No-severe (n = 63) | Severe (n = 32) | P1 | R1 | P3 | No (n = 70) | Yes (n = 25) | P2 | R2 | P4 | ||
Age, Median (range)-years | 49.0 (39.0–58.0) | 49.0 (41.0–57.0) | 50.5 (38.3–58.8) | 0.791 | 0.023 | 0.789 | 49.0 (40.8–56.3) | 52.0 (37.5–63.0) | 0.413 | 0.070 | 0.410 |
Age groups-No., % | 0.376 | −0.026 | 0.794 | 0.120 | 0.022 | 0.820 | |||||
<40 years (n = 24) | 24/95 (25.3) | 14/63 (22.2) | 10/32 (31.3) | 16/70 (22.9) | 8/25 (32.0) | ||||||
14/24 (58.3) | 10/24 (41.7) | 16/24 (66.7) | 8/24 (33.3) | ||||||||
40–60 years (n = 54) | 54/95 (56.8) | 39/63 (61.9) | 15/32 (46.9) | 44/70 (62.9) | 10/25 (40.0) | ||||||
39/54 (72.2) | 15/54 (27.8) | 44/52 (81.5) | 10/52 (18.5) | ||||||||
>60 years (n = 17) | 17/95 (17.9) | 10/63 (15.9) | 7/32 (21.9) | 10/70 (14.3) | 7/25 (28.0) | ||||||
10/17 (58.8) | 7/17 (41.2) | 10/17 (58.8) | 7/17 (41.2) | ||||||||
Age groups-No., % | 0.192 | 0.143 | 0.164 | 0.061 | 0.203 | 0.049 | |||||
40–60 years (n = 54) | 54/95 (56.8) | 39/63 (61.9) | 15/32 (46.9) | 44/70 (62.9) | 10/25 (40.0) | ||||||
39/54 (72.2) | 15/54 (27.8) | 44/54 (81.5) | 10/54 (18.5) | ||||||||
<40 years or >60 years (n = 41) | 41/95 (43.2) | 24/63 (38.1) | 17/32 (53.1) | 26/70 (37.1) | 15/25 (60.0) | ||||||
24/41 (58.5) | 17/41 (41.5) | 26/41 (63.4) | 15/41 (36.6) | ||||||||
Sex -No., % | 0.195 | 0.142 | 0.171 | 0.360 | 0.099 | 0.338 | |||||
Female (n = 42) | 42/95 (44.2) | 31/63 (49.2) | 11/32 (34.4) | 33/70 (44.2) | 9/25 (36.0) | ||||||
31/42 (73.8) | 11/42 (26.2) | 33/42 (78.6) | 9/42 (21.4) | ||||||||
Male (n = 53) | 53/95 (55.8) | 32/63 (50.8) | 21/32 (65.6) | 37/70 (55.8) | 16/25 (64.0) | ||||||
32/53 (60.4) | 21/53 (39.6) | 37/53 (69.8) | 16/53 (30.2) | ||||||||
Highest temperature during hospitalization -No., % | 0.002 | 0.362 | <0.001 | 0.001 | 0.383 | <0.001 | |||||
<37 °C (n = 8) | 8/95 (8.4) | 7/63 (11.1) | 1/32 (3.1) | 8/70 (11.4) | 0/25 (0.0) | ||||||
7/8 (87.5) | 1/8 (12.5) | 8/8 (100.0) | 0/8 (0.0) | ||||||||
37–38 °C (n = 19) | 19/95 (20.0) | 17/63 (27.0) | 2/32 (6.3) | 17/70 (24.3) | 2/25 (8.0) | ||||||
17/19 (89.5) | 2/19 (10.5) | 17/19 (89.5) | 2/19 (10.5) | ||||||||
38–39 °C (n = 35) | 35/95 (36.8) | 25/63 (39.7) | 10/32 (31.3) | 29/70 (41.4) | 6/25 (24.0) | ||||||
25/35 (71.4) | 10/35 (28.6) | 29/35 (82.9) | 6/35 (17.1) | ||||||||
>39 °C (n = 33) | 33/95 (34.7) | 14/63 (22.2) | 19/32 (59.4) | 16/70 (22.9) | 17/25 (68.0) | ||||||
14/33 (42.4) | 19/33 (57.6) | 16/33 (48.5) | 17/33 (51.5) |