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Table 2 The laboratory data in different groups

From: Association between cytokine profiles and lung injury in COVID-19 pneumonia

 

Overall (n = 106)

COVID-19 without pneumonia/Mild (n = 12)

COVID-19 with pneumonia(n = 94)

p –values

Moderate (n = 69)

Severe (n = 25)

p –values

White-cell count, ×109/L

6.12 ± 2.29

5.80 ± 1.46

6.16 ± 2.38

0.618

6.03 ± 2.17

6.49 ± 2.92

0.615

Neutrophil count,× 109/L

3.98 ± 2.14

3.44 ± 1.16

4.05 ± 2.23

0.357

3.77 ± 2.02

4.81 ± 2.64

0.075

Lymphocyte count, ×109/L

1.50 ± 0.68

1.78 ± 0.54

1.46 ± 0.69

0.128

1.59 ± 0.67

1.12 ± 0.66

0.003

Hemoglobin, g/L

128.16 ± 21.07

132.17 ± 13.70

127.65 ± 21.83

0.487

130.71 ± 21.13

119.20 ± 21.91

0.049

PLT, ×109/L

228.16 ± 91.20

215.08 ± 59.31

229.83 ± 94.60

0.600

234.59 ± 81.12

216.68 ± 125.64

0.615

ALT, U/L

24.50 (13.75–40.25)

24.50 (10.75–39.75)

24.50 (14.00–41.75)

0.654

25.00 (13.00–40.50)

24.00 (14.00–42.50)

0.883

AST, U/L

22.50 (15.00–32.25)

21.50 (15.50–27.50)

23.00 (15.25–35.25)

0.460

20.00 (14.50–52.00)

24.00 (15.50–46.00)

0.313

CK,U/L (n = 105)

76.09 ± 40.77

84.58 ± 34.67

74.99 ± 41.53

0.227

71.31 ± 36.51

85.00 ± 52.41

0.268

CK-MB, ng/mL (n = 105)

1.95 ± 4.49

0.67 ± 0.33

2.12 ± 4.75

0.083

1.08 ± 1.78

4.95 ± 8.14

< 0.001

LDH, U/L

193.00 (159.75–241.25)

180.00 (157.75–200.25)

196.50 (160.75–260.75)

0.214

190.00 (155.00–235.00)

239.00 (182.00–672.80)

0.007

APTT, s

37.65 (35.55–40.70)

36.90 (35.33–39.53)

37.90 (35.60–41.20)

0.440

38.30 (35.65–41.20)

36.50 (32.25–40.50)

0.085

PT, s

13.40 (12.80–13.93)

13.20 (12.90–13.68)

13.40 (12.83–14.00)

0.321

13.40 (12.90–14.00)

13.20 (11.85–14.30)

0.281

d-dimer, μg/mL

0.06 (0.05–0.08)

0.22 (0.22–0.22)

0.37 (0.22–0.81)

0.009

0.28 (0.22–0.64)

0.70 (0.32–1.50)

< 0.001

FIB, g/L

3.96 ± 1.60

3.05 ± 0.54

4.07 ± 1.65

< 0.001

3.78 ± 1.47

4.89 ± 1.87

0.001

Hs-CRP, mg/L (n = 98)

2.30 (0.68–8.40)

0.90 (0.33–1.83)(86)

2.45 (0.98–11.85)

0.008

2.25 (0.60–8.75)

3.95 (2.30–47.80)

0.002

PCT, ng/ml (n = 97)

0.06 (0.05–0.08

0.06 (0.05–0.07)

0.07 (0.05–0.09)

0.121

0.06 (0.05–0.08)(62)

0.08 (0.06–0.30)

0.001

  1. Abbreviation: IL interleukin, TNF tumor necrosis factor, Hs-CRP high-sensitivity C-reactive protein, CT computed tomography, PCT procalcitonin, COVID-19 coronavirus disease 2019, PLT platelet, ALT alanine aminotransferase, AST aspartate aminotransferase, CK creatine kinase, LDH lactic dehydrogenase, APTT activated partial thromboplastin time, PT prothrombin time, FIB fibrinogen