The combination of initial markers to predict refractory Mycoplasma pneumoniae pneumonia in Chinese children: a case control study

Table 2 Clinical symptoms and laboratory characteristic of MPP and RMPP patients

Index	CMPP group	RMPP group	t/Χ²	P
Fever (days)	8.05 ± 3.99	9.03 ± 4.17	− 2.43	0.016
Cough (days)	8.26 ± 4.77	10.02 ± 5.28	− 2.82	< 0.01
PT (s)	14.14 ± 0.96	14.22 ± 10.08	− 0.46	0.65
APTT (s)	39.15 ± 2.65	37.24 ± 2.08	0.81	0.42
FIB (g/L)	3.87 ± 0.89	4.44 ± 1.09	− 4.71	< 0.01
TT (seconds)	17.10 ± 1.27	16.04 ± 1.36	0.76	0.45
PCT (ng/mL)	0.16 ± 0.44	0.80 ± 2.61	− 3.05	< 0.01
ESR (mm/h)	44.95 ± 24.22	58.03 ± 30.13	− 3.93	< 0.01
SF (ng/mL)	147.22 ± 122.68	529.82 ± 357.86	− 13.54	< 0.01
D-dimer (μg/mL)	1.46 ± 2.45	6.65 ± 5.66	− 4.35	< 0.01
LDH (U/L)	286.85 ± 101.02	522.08 ± 389.08	− 8.24	< 0.01
LDH-1 (U/L)	49.14 ± 29.61	55.15 ± 14.54	− 1.80	0.07
CK (U/L)	83.46 ± 81.40	209.85 ± 597.36	− 3.05	< 0.01
CK-MB (U/L)	19.71 ± 12.62	48.23 ± 226.65	− 1.83	0.07
TP (g/L)	42.12 ± 38.52	31.91 ± 4.25	2.46	0.01
ALB (g/L)	63.79 ± 4.82	63.71 ± 41.22	0.03	0.98
GLB (g/L)	27.59 ± 14.78	29.74 ± 23.39	− 0.95	0.34
CHO (mmol/L)	3.50 ± 0.70	3.06 ± 0.76	4.76	< 0.01
ALT (U/L)	22.09 ± 47.09	43.14 ± 49.45	− 3.43	< 0.01
AST (U/L)	30.69 ± 21.64	53.86 ± 44.73	− 6.00	< 0.01
WBC (10⁹/L)	10.27 ± 37.17	9.97 ± 4.60	0.07	0.94
LYM (10⁹/L)	2.83 ± 10.25	2.18 ± 1.56	0.58	0.56
NEP (10⁹/L)	5.07 ± 4.80	6.88 ± 3.91	− 3.14	< 0.01
NLR	2.62 ± 1.55	4.14 ± 2.52	− 6.40	< 0.01
HGB (g/L)	125.22 ± 76.04	115.93 ± 12.21	1.14	0.26
PLT (10⁹/L)	325.48 ± 106.48	327.53 ± 151.77	− 0.134	0.89
PM	32.91 ± 13.25	33.09 ± 19.19	− 0.09	0.93
CRP (mg/L)	19.03 ± 24.50	62.80 ± 52.15	− 7.54	< 0.01

RMPP refractory Mycoplasma pneumoniae pneumonia, CMMP common Mycoplasma pneumoniae pneumonia, PT prothrombin time, APTT activated partial prothrombin time, TT clotting time, ESR erythrocyte sedimentation rate, PCT procalcitonin, SF serum ferritin, LDH lactate dehydrogenase, LDH1 lactate dehydrogenase isoenzymes, CK creatine kinase, CK-MB creatine kinase isoenzymes, TP total protein, ALB albumin, GLB globulin, CHO cholesterol, ALT alanine aminotransferase, AST aspartate aminotransferase, WBC leucocyte count, LYM leukomonocyte count, NEP neutrophil granulocyte count, NLR neutrophil count/lymphocyte count ratio, HGB hemoglobin concentration, PLT platelet count, PM platelet count/mean platelet volume, CRP C-reactive protein

ISSN: 1465-993X