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Table 2 Comparation between derivation and validation cohorts

From: Developing a scoring tool to estimate the risk of deterioration for normotensive patients with acute pulmonary embolism on admission

 

Derivation cohort

(n = 554)

Validation cohort

(n = 291)

p-value

Sex (male)

267 (48.2%)

153 (52.6%)

0.23

Age (years)

60.43 ± 14.95

59.32 ± 16.30

0.33

Heart rate (beats/min)

86.11 ± 17.76

87.46 ± 17.89

0.30

Systolic pressure (mmHg)

126.92 ± 18.27

125.30 ± 18.09

0.22

RV dysfunction

161 (29.0%)

79 (27.1%)

0.56

c-Tn I (μg/L)

0.11 ± 0.54

0.10 ± 0.29

0.79

NT-pro BNP (pg/mL)

1638.25 ± 3958.77

1373.61 ± 2980.96

0.28

CPA embolism

141 (25.5%)

68 (23.4%)

0.50

Saddle-CPA embolism

38 (6.9%)

24 (8.2%)

0.46

RV short-axis diameter (mm)

39.26 ± 7.605

39.11 ± 6.97

0.77

LV short-axis diameter (mm)

40.58 ± 7.65

41.08 ± 7.52

0.35

RV4-chamber diameter (mm)

36.22 ± 7.21

36.68 ± 7.68

0.41

LV 4-chamber diameter (mm)

39.50 ± 7.26

39.41 ± 7.55

0.86

RA 4-chamber diameter (mm)

45.50 ± 9.38

45.32 ± 9.27

0.79

LA 4-chamber diameter (mm)

34.95 ± 8.38

34.61 ± 8.77

0.58

RV/LV short-axis diameter ratio

1.00 ± 0.31

0.98 ± 0.27

0.34

RV/LV 4-chamber diameter ratio

0.95 ± 0.28

0.97 ± 0.35

0.37

RA/LA 4-chamber diameter ratio

1.39 ± 0.52

1.40 ± 0.51

0.76

Bova score

 Low risk

445 (80.3%)

236 (81.1%)

0.79

 Intermediate-low risk

66 (11.9%)

36 (12.3%)

0.85

 Intermediate-high risk

43 (7.8%)

19 (6.5%)

0.51

2019 ESC algorithm

 Low risk

330 (59.6%)

173 (59.5%)

0.97

 Intermediate-low risk

112(20.2%)

60 (20.6%)

0.89

 Intermediate-high risk

112(20.2%)

58 (19.9%)

0.92

 Adverse outcomes

54(9.7%)

27(9.3%)

0.83

  1. c Tn-I cardiac troponin I, NT-pro BNP N-terminal pro-brain natriuretic peptide, CPA central pulmonary artery, RV right ventricle, LV left ventricle, RA right atrium, LA left atrium, ESC European Society of Cardiology