Fig. 6
From: Hermansky-Pudlak syndrome-2 alters mitochondrial homeostasis in the alveolar epithelium of the lung
Mitochondrial biogenesis factors are increased in HPS-2 lung tissues. a, b Transcript levels for Pgc1α, Pgc1β, Prc, Nrf1, Tfam, Atp5a, Cox5a, and Cox2 in control and HPS-2-MLE15 cells (n = 4–5, each group). c Mitochondrial DNA content in control and HPS-2-MLE15 cells (n = 5, each group). d Transcript levels for Pgc1α, Pgc1β, Prc, Nrf1, Tfam in lungs of wild-type and HPS-2 mice (n = 5, each group). e Mitochondrial DNA content in lungs of wild-type and HPS-2 mice (n = 6, each group). Student’s t-test. *P < 0.05, **P < 0.01 vs. control group