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Table 2 Comparison of autonomic parameters before transplantation (T0), 10–15 days after transplant (T1) and 6 months after surgery (T2). Autonomic parameters were obtained in supine position

From: Effects of bilateral lung transplantation on cardiac autonomic modulation and cardiorespiratory coupling: a prospective study

 

T0

n = 14

T1

n = 14

T2

n = 14

p

Heart rate, median (IQR) bpm

85 (74–99)

91 (87–96)

76 (71–87)

0.099

Spectral analysis, median (IQR)

    

 Total power, ms2

898 (345–1163)

156 (49–284)a

204 (85–427)a

 < 0.001

 LFnu

48 (26–69)

42 (14–78)

66 (43–79)

0.508

 HFnu

21 (9–66)

19 (8–58)

23 (16–44)

0.94

 LF/HF

2.21 (0.37–4.13)

2.64 (0.42–8.44)

2.89 (1.00–5.24)

0.477

 RR-RESP HFk2

0.86 (0.6–0.92)

0.75 (0.24–0.88)

0.91 (0.62–0.95)

0.408

 RESP HF, Hz

0.34 (0.31–0.38)

0.33 (0.28–0.36)

0.29 (0.26–0.33)

0.212

Symbolic analysis, median (IQR)

    

 0 V%

24 (11–36)

52 (32–59)a

45 (42–54)a

0.002

 2LV%

5 (2–11)

2 (1–4)

3 (2–4)

0.076

 2UV%

19 (12–25)

11 (8–13)

9 (7—12)a

0.015

Entropy measures, median (IQR)

    

 CE

0.95 (0.9–1.01)

0.70 (0.56–0.89)a

0.8 (0.72–0.87)

0.025

 Ro

0.35 (0.28–0.4)

0.47 (0.41–0.49)a

0.46 (0.42–0.52)a

0.006

  1. n number, LTx transplant list, IQR 25–75, interquartile range, bpm beats per minute, ms2 milliseconds2, LF low frequency, HF high frequency, nu normalized, LF/HF sympatho-vagal balance, RR R–R interval, RESP respiratory, K2 coherence, Hz Hertz, CE conditional entropy, Ro index of regularity
  2. aDifferences from T0