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Table 2 ROC analysis of different indicators in distinguishing ATB from non-TB in suspected patients with positive T-SPOT results

From: The TBAg/PHA ratio in T-SPOT.TB assay has high prospective value in the diagnosis of active tuberculosis: a multicenter study in China

 

Cutoff value

Sensitivity

Specificity

PLR

P value

ESAT-6 sfc

 > 20

76.4

76.0

3.2

P < 0.0001

CFP-10 sfc

 > 40

66.4

88.7

5.9

P < 0.0001

PHA sfc

 < 214

37.3

85.8

2.6

P < 0.0001

  1. ATB including confirmed ATB and probable ATB
  2. ROC receiver operating characteristic, ATB active tuberculosis, ESAT-6 early secreted antigenic target 6, CFP-10 culture filtrate protein 10, PHA phytohaemagglutinin, sfc spot-forming cells