Fig. 8From: TIPE2 inhibits PDGF-BB-induced phenotype switching in airway smooth muscle cells through the PI3K/Akt signaling pathwayKnockdown of TIPE2 aggravated PDGF-BB-induced activation of PI3K/Akt signaling pathway in ASMCs. ASMCs were transfected with si-TIPE2 or si-NC for 48 h and then treated with PDGF-BB. The levels of TIPE2, PI3K, p-PI3K, Akt, and p-Akt were determined by Western blotting. Control group, *p < 0.05, vs. the si-NC + PDGF-BB group, #p < 0.05Back to article page