Table 1 Spirometry, impulse oscillometry and exhaled nitric oxide results

Spirometry

 FVC, l

  Mean ± SD

4.53 ± 0.96

− 0.18 ± 0.88

4.45 ± 1.01

− 0.30 ± 0.96

− 1.8 ± 2.3

  Median (IQR)

4.47 (3.99–4.88)

− 0.10 (− 0.87–0.24)

4.28 (3.87–5.02)

− 0.13 (− 1.09–0.28)

− 2.4 (− 3.5–0.0)

  Range

2.45–6.46

− 1.28–1.65

2.39–6.54

− 1.67–1.78

− 5.3–2.9

 FEV₁, l

  Mean ± SD

3.59 ± 0.71

0.09 ± 0.91

3.65 ± 0.74

0.21 ± 0.94

1.7 ± 1.9

  Median (IQR)

3.55 (3.23–3.99)

0.23 (− 0.59–0.73)

3.63 (3.21–4.15)

0.31 (− 0.44–0.92)

2.2 (− 0.3–3.3)

  Range

1.96–5.28

− 1.66–2.15

1.97–5.37

− 1.62–2.31

− 2.5–4.7

 FEV₁/FVC, %

  Mean ± SD

79.57 ± 4.24

0.57 ± 0.99

82.45 ± 4.89

1.11 ± 1.06

3.6 ± 2.1

  Median (IQR)

81.55 (75.78–82.72)

0.89 (− 0.43–1.39)

82.34 (79.25–85.97)

0.91 (− 0.07–2.15)

3.2 (2.1–5.8)

  Range

68.88–84.62

− 0.93–1.75

71.10–90.53

− 0.52–2.62

− 0.1–7.0

 MMEF, l·s⁻¹

  Mean ± SD

3.49 ± 0.95

0.49 ± 1.13

3.95 ± 1.03

1.02 ± 1.23

13.6 ± 6.6

  Median (IQR)

3.49 (2.68–4.09)

0.59 (− 0.41–1.06)

3.99 (3.04–4.77)

0.94 (− 0.07–1.79)

13.4 (9.3–16.0)

  Range

1.87–5.57

− 1.48–2.81

2.07–6.06

− 0.95–3.32

− 0.9–26.7

 MEF₅₀, l·s⁻¹

  Mean ± SD

4.23 ± 1.10

0.44 ± 1.04

4.83 ± 1.07

0.99 ± 0.97

15.9 ± 14.3

  Median (IQR)

4.02 (3.46–4.91)

0.61 (− 0.21–1.00)

4.78 (3.98–5.63)

1.25 (0.37–1.42)

13.2 (7.5–19.0)

  Range

2.21–6.54

− 1.28–2.45

2.78–7.03

− 0.76–2.86

− 10.4–49.9

IOS

 R5, kPa·l⁻¹·s

  Mean ± SD

0.30 ± 0.09

− 0.06 ± 1.00

0.27 ± 0.07

− 0.60 ± 1.58

− 7 ± 12

  Median (IQR)

0.28 (0.24–0.39)

− 0.01 (− 0.51–0.38)

0.27 (0.23–0.32)

− 0.29 (− 0.95–0.04)

− 8 (− 15–3)

  Range

0.13–0.45

− 1.89–2.49

0.12–0.39

− 5.78–1.98

− 23–18

 R5-20, kPa·l⁻¹·s

  Mean ± SD

0.03 ± 0.03

− 0.98 ± 0.98

0.03 ± 0.02

− 1.04 ± 1.55

13 ± 73

  Median (IQR)

0.04 (0.01–0.05)

− 0.79 (− 1.55 to − 0.45)

0.02 (0.01–0.06)

− 0.86 (− 1.73 to − 0.42)

− 10 (− 42–60)

  Range

− 0.02–0.09

− 2.94–1.11

− 0.02–0.06

− 4.41–3.58

− 95–179

 X5, kPa·l⁻¹·s

  Mean ± SD

− 0.08 ± 0.03

1.07 ± 1.39

− 0.07 ± 0.03

1.69 ± 2.00

− 16 ± 21

  Median (IQR)

− 0.08 (− 0.09 to − 0.06)

0.76 (0.05–1.81)

− 0.07 (− 0.08 to − 0.05)

1.08 (0.54–2.19)

− 16 (− 31–1)

  Range

− 0.14 to − 0.03

− 0.74–5.05

− 0.13 to − 0.01

− 0.99–7.10

− 59–21

 AX, kPa·L⁻¹

  Mean ± SD

0.27 ± 0.19

− 0.32 ± 0.66

0.19 ± 0.13

− 0.10 ± 1.52

− 22 ± 30

  Median (IQR)

0.29 (0.10–0.41)

− 0.18 (− 0.60–0.11)

0.18 (0.08–0.29)

− 0.37 (− 0.63 to − 0.19)

− 26 (− 46 to − 6)

  Range

0.04–0.72

− 2.46–0.67

0.01–0.46

− 1.22–6.13

− 75–53

Exhaled NO

 FE_NO, ppb

  Mean ± SD

21.7 ± 6.9

N/A

N/A

N/A

N/A

  Median (IQR)

21.8 (17.0–28.2)

N/A

N/A

N/A

N/A

  Range

9.1–31.2

N/A

N/A

N/A

N/A

 NO_alv, ppb

  Mean ± SD

1.4 ± 1.0

− 1.19 ± 0.58

N/A

N/A

N/A

  Median (IQR)

1.4 (0.6–1.7)

− 1.20 (− 1.69 to − 1.02)

N/A

N/A

N/A

  Range

0.2–3.9

− 1.93–0.30

N/A

N/A

N/A