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Table 1 Characteristics of study subjects by sex

From: Blood leukocyte count as a systemic inflammatory biomarker associated with a more rapid spirometric decline in a large cohort of iron and steel industry workers

Variable

Male

Female

P a

n

M ± SD

Median (Q1, Q3)

n

M ± SD

Median (Q1, Q3)

Age (year)

6188

34.4 ± 9.2

34 (26, 42)

1325

34.7 ± 7.6

35 (29, 40)

0.014

Han Ethnic (n, %)

6188

6129, 99.1

 

1325

1312, 99.0

 

0.972

Height (cm)

6110

171.5 ± 5.5

171 (168, 175)

1295

160.1 ± 5.2

160 (156, 164)

 < 0.001

BMI (kg/m2)

6110

24.5 ± 3.6

24.38 (21.9, 26.9)

1295

22.3 ± 3.1

21.87 (20.03, 23.88)

 < 0.001

Current smoker (n, %)

6188

3034, 49.0

 

1325

0, 0

 

NC

Packyears

3034

11.0 ± 10.4

7.5 (3.0, 18.0)

0

NA

NA

NC

Years of dust exposure (year)

6188

12.6 ± 9.7

10.5 (3.3, 20.8)

1325

13.5 ± 8.2

13.9 (5.3, 19.9)

 < 0.001

Time in cohort (year)

6188

5.4 ± 2.8

6.00 (3.9, 8.1)

1325

5.3 ± 2.6

6.0 (3.9, 7.9)

0.184

TWEI

6188

0.93 ± 0.74

1.00 (0.00, 1.5)

1325

0.64 ± 0.74

0.19 (0.00, 1.00)

 < 0.001

NO. of spirometry (n)

6188

3.5 ± 1.4

4 (2, 5)

1325

3.4 ± 1.2

3 (2, 4)

0.004

Spirometry

       

 FEV1 (ml/s)

6188

3838.6 ± 622.5

3800 (3410, 4240)

1325

2828.7 ± 440.2

2800 (2520, 3090)

 < 0.001

 FEV1% predicted (%)

6105

102.2 ± 14.3

100.7 (92.0, 111.0)

1295

101.5 ± 14.6

100.0 (90.9, 109.9)

0.098

 FVC (ml)

6188

4211.4 ± 623.0

4150 (3730, 4650)

1325

3101.5 ± 467.6

3060 (2750, 3400)

 < 0.001

 FVC% predicted (%)

6105

103.1 ± 14.2

101.5 (92.5, 112.3)

1295

106.0 ± 14.7

104.4 (94.9, 115.4)

 < 0.001

 FEV1/FVC (%)

6188

91.3 ± 6.2

91.3 (87.0, 96.5)

1325

91.3 ± 5.9

91.2 (87.5, 95.9)

0.702

White blood cell count

       

 WBC (109 cells per L)

5949

6.23 ± 1.63

6.0 (5.1, 7.1)

1290

5.31 ± 1.41

5.1 (4.3, 6.1)

 < 0.001

 NEU (109 cells per L)

5945

4.00 ± 1.35

3.8 (3.1, 4.7)

1287

3.43 ± 1.13

3.3 (2.6, 4.0)

 < 0.001

 LYM (109 cells per L)

5945

21.97 ± 0.54

1.9 (1.6, 2.3)

1287

1.67 ± 0.51

1.6 (1.4, 1.9)

 < 0.001

 MID (109 cells per L)

5945

0.26 ± 0.14

0.2 (0.2, 0.3)

1287

0.21 ± 0.11

0.2 (0.1, 0.3)

 < 0.001

 HGB (g/L)

5035

149.35 ± 12.43

150 (141, 158)

1174

123.86 ± 13.16

124 (117, 133)

0.194

  1. The prediction reference equation for Asian adults: (1) FVC (ml): (27.63–0.112*age) *height for male, (21.78–0.101*age) *height for female; (2) FEV1 (ml): 34.4*height-33*age-1000 for male, 26.7*height-27*age-540 for female
  2. M  mean, SD  standard deviation, Q  quartile, BMI  body mass index, TWEI  time-weighted exposure intensity, FEV1  forced expiratory volume in 1 s, FVC  forced vital capacity, WBC  white blood count, NEU  neutrophilicgranulocyte, LYM  lymphocyte, MID  mid-range absolute count
  3. aT-test for all variables between sexes except for ethnicity which used χ2 Test
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Respiratory Research

ISSN: 1465-993X

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