Fig. 3
From: MUC5B regulates goblet cell differentiation and reduces inflammation in a murine COPD model
MUC5B−/− mice have decreased SPDEF expression. MUC5B+/+ mice (n = 15 per group) and MUC5B−/− mice (n = 10 per group). a SPDEF immunohistochemical staining and IHC score. b STAT6 immunohistochemical staining and positive cell percentage. c FOXA2 immunohistochemical staining and positive cell percentage. d SPDEF western blot and grayscale analysis. e STAT6 western blot and grayscale analysis. f FOXA2 western blot and grayscale analysis. “-” indicates a significant difference between two groups. “*” indicates a significant difference; ***P < 0.001, **P < 0.01, *P < 0.05 compared to smoke-exposed MUC5B+/+ mice