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Table 1 Characteristics of all subjects analyzed in the present study

From: The use of exhaled air analysis in discriminating interstitial lung diseases: a pilot study

 

Controls

IPF patients

CTD-ILD patients

Significance Ctrls vs. IPF

Significance Ctrls vs. CTD-ILD

Significance IPF vs. CTD-ILD

Number of subjects

51

53

51

ns

ns

Ns

Age (yrs. ± STD)

53 (± 10)

69 (± 9)

57 (± 12)

5.8*10–6

ns

1*10–6

% male

68

75

26

ns

0.002

1.63*10–6

% smokers ex/current

35/16

60/0

24/4

  

0.02

mMRC class 0

44

5

5

  

ns

mMRC class 1

7

29

22

  

ns

mMRC class 2

0

12

16

  

ns

mMRC class 3

0

6

5

  

ns

mMRC class 4

0

1

3

  

ns

VC (% ± STD)

NA

77 (± 22)

78 (± 23)

  

ns

TLC (% ± STD)

NA

71 (± 15)

76 (± 15)

  

ns

FRC (% ± STD)

NA

74 (± 17)

78 (± 15)

ns

ns

0.001

FEV1 (% ± STD)

NA

80 (± 22)

78 (± 25)

ns

ns

0.0008

DLCO (% ± STD)

NA

49 (± 17)

49 (± 17)

ns

ns

0.03

PaO2 (± STD mm Hg)

NA

75 (± 9)

80 (± 12)

  

ns

PaC02 (± STD mm Hg)

NA

41 (± 4)

39 (± 4)

  

ns

6MWD (% ± STD)

NA

88 (± 20)

78 (± 20)

  

ns

  1. Continuous variables were displayed as mean and standard deviation or percentages. Lung function parameters are displayed as a percentage of the predicted value based on age and gender. mMRC modified medical research council dyspnea scale VC vital capacity, TLC total lung capacity, FRC functional residual capacity, FEV1 forced expiratory volume in 1 s; DLCO diffusing capacity for carbon monoxide, PaO2 and PaCO2 oxygen and carbon dioxide pressure in arterial blood, 6MWD six-minute walk distance, NA not available. Significances were calculated using a Student’s t-test (the data are normally distributed based on Lilliefors test) in combination with False Discovery Rate correction. ns not significant