Table 4 Laboratory parameters and clinical characteristics of the mild and severe COVID-19 patients
From: Decreased level of serum NT-proCNP associates with disease severity in COVID-19
Characteristics | Mild COVID-19 (n = 20) | Severe COVID-19 (n = 12) | p value |
|---|---|---|---|
Clinical characteristics | |||
Dyspnoea n (%) | 8 (40) | 11 (92) | < 0.01 |
O2 supply L/min (IQR) | 0 (0) | 13.5 (9) | < 0.01 |
GCS on admission (SD) | 15 (0) | 14 (3.46) | 0.19 |
Fever n (%) | 15 (75) | 10 (83) | 0.68 |
Laboratory parameters | |||
Leukocytes 103/µL (IQR) | 4.1 (2.6) | 7.2 (5.8) | 0.02 |
Platelets 103/µL (IQR) | 180 (61) | 195 (132) | 0.24 |
Haemoglobin g/dL (IQR) | 12.9 (2.3) | 11.1 (2.5) | 0.03 |
CRP mg/L (IQR) | 15.5 (56) | 160 (162) | < 0.01 |
PCT ng/mL (IQR) | 0.07 (0.06) | 0.38 (1.1) | < 0.01 |
IL-6 pg/mL (IQR) | 13.8 (37.3) | 104 (829.6) | < 0.01 |
GOT U/L (IQR) | 37.5 (39.5) | 44 (15) | 0.47 |
GPT U/L (IQR) | 31 (18) | 26 (21) | 0.45 |
GGT U/L (IQR) | 44 (62) | 95 (95) | 0.03 |
LDH U/L (IQR) | 260 (173) | 454 (158) | < 0.01 |
Bilirubin mg/dL (IQR) | 0.4 (0.3) | 0.4 (0.3) | 0.56 |
Creatinine mg/dL (IQR) | 0.92 (0.45) | 1.01 (0.73) | 0.31 |
Ca2+ mmol/L (SD) | 1.17 (0.06) | 1.15 (0.09) | 0.54 |
Na+ mmol/L (SD) | 137 (3.8) | 139 (5.3) | 0.14 |
K+ mmol/L (SD) | 4.16 (0.73) | 4.26 (0.56) | 0.68 |
CK U/L (IQR) | 72 (123) | 60.5 (72.5) | 0.25 |
Troponin T ng/L (IQR) | 6.4 (5) | 12.9 (23.8) | < 0.01 |
NT-proBNP pg/mL (IQR) | 106 (312) | 597 (1310) | < 0.01 |
Myoglobin ng/mL (IQR) | 64 (33) | 89 (50) | 0.14 |
D-dimer mg/L (IQR) | 1.17 (1.4) | 1.1 (2.1) | 0.67 |
vWF activity % (IQR) | 240 (99) | 393 (82) | 0.06 |
vWF antigen % (IQR) | 277 (143) | 414 (3) | 0.01 |
Fibrinogen mg/dL (IQR) | 303 (119) | 688 (234) | < 0.01 |
CNP and furin measurements | |||
NT-proCNP pmol/L (IQR) | 18.8 (11.4) | 6.1 (6.6) | < 0.01 |
Furin pg/mL (IQR) | 10 (54) | 26 (134) | 0.69 |