Fig. 4
From: Molecular mechanisms and treatment responses of pulmonary fibrosis in severe COVID-19
Circulating procollagen type III concentrations and clinical parameters. Differences between the pulmonary fibrosis (PF)- and no-PF-groups in kinetics of circulating procollagen type III (PIIINP) in a pre-DEXA-cohort and b DEXA-cohort, dynamic lung compliance in c pre-DEXA-cohort and d DEXA-cohort, ventilatory ratio in e pre-DEXA-cohort and f DEXA-cohort, and PaO2/FiO2 ratio in e pre-DEXA-cohort and f DEXA-cohort within 9 days (PIIINP) or 8 days (ventilatory parameters) prior to and 12 days following the alignment day (PF-day 0, start of prednisone treatment in the PF-groups). P-values on the left and the right of each panel reflect between-group differences over time for the days prior to and following PF-day 0, respectively, and were calculated using linear mixed models analysis (time * group interaction factor). Data presented as geometric mean with 95% confidence intervals. *p-value < 0.05 on the corresponding timepoint, calculated using Sidak’s post-hoc multiple comparisons tests