Table 2 The concentration of acylcarnitines, cholesterol, and oxysterols in erythrocytes of healthy volunteers and hospitalized COVID-19 cases. p-Values calculated at probability ± 0.05, n = 30 of each group
From: Accumulation of oxysterols in the erythrocytes of COVID-19 patients as a biomarker for case severity
tR, min | Name | Exact mass | Precursor ion, + m/z | Healthy, concentration μg/mL ± SD | COVID-19, concentration, μg/mL ± SD | p-value | ** | ||
|---|---|---|---|---|---|---|---|---|---|
25.82 | O-Palmitoleoyl-L-carnitine | 397.32 | 398.32 | 0.19 |  ± 0.22 | 0.35 |  ± 0.20 | 0.01 | ↑ |
30.94 | Palmitoyl-L-carnitine | 399.33 | 400.33 | 1.96 |  ± 0.69 | 3.88 |  ± 2.01 | 0.00 | ↑ |
28.71 | Linoleoyl-L-carnitine | 423.33 | 424.34 | 0.91 |  ± 0.44 | 2.20 |  ± 1.24 | 0.00 | ↑ |
32.52 | Oleoyl-L-carnitine | 425.35 | 426.36 | 2.00 |  ± 0.65 | 4.96 |  ± 2.67 | 0.00 | ↑ |
37.64 | Stearoyl-L-carnitine | 427.36 | 428.38 | 1.07 |  ± 0.36 | 1.64 |  ± 0.69 | 0.00 | ↑ |
16.72 | 3-Hydroxyoleoylcarnitine | 441.35 | 442.36 | 0.01 |  ± 0.00 | 0.06 |  ± 0.03 | 0.00 | ↑ |
32.55 | Oleoyl-L-carnitine-d9, IS1 | 434.35 | 435.37 | – |  | – |  | – | – |
60.61 | Cholesterol | 386.35 | 369.37 | 0.06 |  ± 0.01 | 0.19 |  ± 0.09 | 0.00 | ↑ |
49.11 | 4,6-Cholestadien-3-one | 382.32 | 383.34 | 0.19 |  ± 0.05 | 0.95 |  ± 0.43 | 0.00 | ↑ |
38.52 | 4β-Hydroxycholesterol-4-acetate | 444.36 | 367.38 | 0.47 |  ± 0.16 | 1.83 |  ± 1.13 | 0.00 | ↑ |
38.82 | 4β-Hydroxycholesterol | 402.35 | 385.37 | 0.17 |  ± 0.13 | 0.52 |  ± 0.37 | 0.00 | ↑ |
50.28 | 4-Cholestenone | 384.34 | 385.36 | 0.15 |  ± 0.13 | 1.50 |  ± 0.85 | 0.00 | ↑ |
40.19 | 7-Ketocholesterol | 400.33 | 401.33 | 3.94 |  ± 1.14 | 18.56 |  ± 10.69 | 0.00 | ↑ |
60.82 | Cholesterol-d6, IS2 | 392.35 | 375.35 | – |  | – |  | – | – |
40.22 | 7-Ketocholesterol-d7, IS3 | 407.33 | 408.34 | – |  | – |  | – | – |