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Fig. 3 | Respiratory Research

Fig. 3

From: Prolyl oligopeptidase inhibition ameliorates experimental pulmonary fibrosis both in vivo and in vitro

Fig. 3

Effect of KYP-2047 on IκBα/NF-κB pathway and inflammation. Western blot analyses showed that KYP-2047 was able to modulate IκBα/NF-κB (respectively B and A); additionally, treatment with KYP-2047 reduced IL-18 (C) compared to LPS group. ELISA kit showed that KYP-2047 reduced TNF-α (D) expression compared to LPS group. Data are representative of at least three independent experiments. One way ANOVA test **p < 0.01 vs CTR; ***p < 0.001 vs CTR; #p < 0.05 vs LPS; ###p < 0.001 vs LPS

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