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Table 2 Treatment patterns at baseline for all patients and stratified by prompt or delayed FF/UMEC/VI initiation

From: Benefit of prompt initiation of single-inhaler fluticasone furoate, umeclidinium, and vilanterol (FF/UMEC/VI) in patients with COPD in England following an exacerbation: a retrospective cohort study

 

Total

(N = 1599)

Prompt

(0–30 days)

(N = 393)

Delayed

(31–180 days)

(N = 1206)

Number of respiratory therapy classes at baseline

   

 Mean (SD)

3.0 (1.22)

3.1 (1.14)

3.0 (1.24)

Class of respiratory therapy at baseline*, n (%)

   

 SABA

1426 (89.2)

358 (91.1)

1068 (88.6)

 MITT

1005 (62.9)

259 (65.9)

746 (61.9)

 ICS/LABA

952 (59.5)

233 (59.3)

719 (59.6)

 LAMA

814 (50.9)

197 (50.1)

617 (51.2)

 LABA/LAMA

313 (19.6)

101 (25.7)

212 (17.6)

 Methylxanthine

98 (6.1)

27 (6.9)

71 (5.9)

 ICS/SABA

73 (4.6)

14 (3.6)

59 (4.9)

Inhaled therapy regimen immediately prior to index†, n (%)

   

 MITT

731 (45.7)

168 (42.8)

563 (46.7)

 ICS, LABA, or ICS/LABA

352 (22.0)

75 (19.1)

277 (23.0)

 LABA/LAMA

257 (16.1)

91 (23.2)

166 (13.8)

 LAMA

181 (11.3)

49 (12.5)

132 (11.0)

 None of the above regimens

78 (4.9)

10 (2.5)

68 (5.6)

  1. FF/UMEC/VI fluticasone furoate/umeclidinium/vilanterol, SD standard deviation, SABA short-acting β2-agonist, MITT multiple-inhaler triple therapy, ICS inhaled corticosteroid, LABA long-acting β2-agonist, LAMA long-acting muscarinic antagonist, SAMA short-acting muscarinic antagonist, PDE4 phosphodiesterase 4. *In the 12 months prior to indexing; therapy classes are not mutually exclusive. ICS, LABA, SAMA, SAMA/SABA, and PDE4 classes are not reported due to low patient numbers, †Last therapy prior to indexing; regimens are mutually exclusive