Mechanical thrombectomy in intermediate- and high-risk acute pulmonary embolism: hemodynamic outcomes at three months

Table 3 Hemodynamic data

	Pre-procedure Mean ± SD	Post-procedure Mean ± SD	Mean change from pre-procedure^a Mean (95% CI)	p-value*	3 months Mean ± SD	Mean change between post-procedure and 3 months^b Mean (95% CI)	p-values^†
Right heart catheterization
Systolic PAP, mmHg	51.3 ± 11.6 n = 29	37.2 ± 7.6 n = 26	-15.0 (-18.9 to -11.0) n = 26	< 0.001	30.5 ± 7.2 n = 20	-6.4 (-10.0 to -2.9) n = 18	0.002
Diastolic PAP, mmHg	16.4 ± 8.2 n = 29	13.1 ± 5.0 n = 26	-3.8 (-6.6 to -1.1) n = 26	0.008	11.2 ± 5.1 n = 20	-2.9 (-6.3 to 0.4) n = 18	0.079
Mean PAP, mmHg	29.8 ± 9.1 n = 29	21.7 ± 6.4 n = 27	-8.4 (-11.0 to -5.8) n = 27	< 0.001	19.2 ± 5.6 n = 20	-2.7 (-5.7 to 0.3)	0.077
Clinic BP
Systolic BP, mmHg	129 ± 22 n = 29	123 ± 16 n = 29	-6 (-15 to 3) n = 29	0.199	122 ± 13 n = 18	-2 (-12 to 9) n = 18	0.756
Diastolic BP, mmHg	79 ± 19 n = 29	70 ± 11 n = 29	-8.6 (-14 to -3) n = 29	0.005	74 ± 8 n = 18	-1 (-7 to 5)	0.748
Heart rate, b.p.m.	101 ± 20 n = 29	74 ± 10 n = 29	-27 (-35 to -20) n = 29	< 0.001	77 ± 11 n = 18	7 (1 to 14)	0.037
Peripheral oxygen saturation, %	93 ± 7 n = 29	97 ± 2 n = 29	4 (1 to 7) n = 29	0.006
Supplemental oxygen, l/min	7 ± 5 n = 24	2 ± 2 n = 24	-5 (-6 to -3) n = 24	< 0.001
Lactate, mmol/l	2.8 ± 3.0 n = 29	1.0 ± 0.5 n = 29	-1.8 (-2.9 to -0.7) n = 29	0.003

Data are presented as means ± SD or counts (percentages). Before-after changes are summarized as means (95% confidence intervals [CI]). ^†Matched data for change from before discharge to three months of follow-up.
^a Matched data for change from pre-procedure to post-procedure. ^b Matched data for change from post-procedure to three months of follow-up
Abbreviations: PAP, pulmonary artery pressure

ISSN: 1465-993X