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Table 1 Evolution of the lung uptake of [18F]FAPI-74 at days 10 and 16 after instillation

From: Usefulness of FAPα assessment in bronchoalveolar lavage as a marker of fibrogenesis: results of a preclinical study and first report in patients with idiopathic pulmonary fibrosis

 

Day 10

Day 16

Controls (n = 4)

Bleomycin

(n = 7)

p-value

Controls

(n = 5)

Bleomycin

(n = 7)

p-value

SUVmean 40–50 (g/mL)

0.17 ± 0.03

0.26 ± 0.04

0.0029

0.19 ± 0.03

0.27 ± 0.04

0.0037

SUVmean 50–60 (g/mL)

0.15 ± 0.02

0.23 ± 0.04

0.0019

0.17 ± 0.03

0.25 ± 0.05

0.0065

SUVmean 60–70 (g/mL)

0.14 ± 0.02

0.21 ± 0.03

0.0037

0.16 ± 0.03

0.23 ± 0.04

0.0182

SUVmean 70–80 (g/mL)

0.13 ± 0.02

0.20 ± 0.03

0.0064

0.14 ± 0.03

0.21 ± 0.04

0.0379

SUVmean 80–90 (g/mL)

0.12 ± 0.02

0.18 ± 0.03

0.0142

0.13 ± 0.02

0.19 ± 0.04

0.0650

  1. The standardised uptake value (SUVmean) was measured between 40 and 90 min after injection with subanalyses of 10 min. Data are presented as mean ± Standard deviation. Statistical analysis was performed using a Two-Way ANOVA followed by Bonferroni correction test for multiple comparisons. Bold p-value indicate a significant difference
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Respiratory Research

ISSN: 1465-993X

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