Fig. 3From: Circular RNA P4HB promotes glycolysis and tumor progression by binding with PKM2 in lung adenocarcinomacircP4HB promotes LUAD invasion, migration and proliferation in vitro. Schematic illustration showing the siRNA specifically targeting the circP4HB splice junction (A) and the overexpression vector (B); (C, D) showed the efficiency of silencing or overexpressing; (E, F) transwell showed the invasion ability of different circP4HB expression; (G) wound healing assays illustrated circP4HB accelerate the migration of LUADs; (H, I, J) colony formation and CCK8 assays showed circP4HB can increase the proliferation of LUAD cells. (*p < 0.05, **p < 0.01. N.S no significance.)Back to article page