Fig. 1From: Do alternative tobacco products induce less adverse respiratory risk than cigarettes?Schema of 8-week and 12-week animal exposures. Mice were exposed to aerosols from 3 products for 8Â weeks (A) or 12Â weeks (B). Air-exposed animals served as control for each group. Mice exposed for 12Â weeks were vaccinated i.m. at wk5, wk6 and wk7 after the start of exposures, and were given acute intratracheal challenge with NTHI (106 cfus/mouse in 50uL PBS) at the end of the wk12 for 0, 4 and 12Â hBack to article page