Fig. 2From: Amitriptyline inhibits bronchoconstriction and directly promotes dilatation of the airwaysThe effect of amitriptyline on bronchoconstriction is ASM-independent. A Concentration–response curves of PCLS of ASM-knockout and wildtype littermates stimulated with acetylcholine. B Concentration response curves of PCLS of ASM-knockout mice pre-treated with amitriptyline (5 µM). A, B n = 4 in all groups. Graphs represent mean ± SEM; *p < 0.05Back to article page